Lassiter Textbook of Wound Medicine — First Edition

First Edition

Textbook of
Wound Medicine

A Modern Guide to Comprehensive Wound Management

By Lonnie Lassiter, MD

A Physiology-Centered Framework

Chronic wounds fail to heal because of unaddressed biologic barriers, not because of insufficient product use. This textbook reframes wound care around wound biology — not dressings.

The Problem With Product-Driven Care

Chronic wound documentation is frequently fragmented, emphasizing surface appearance and dressing selection over underlying wound biology. This obscures physiologic reasoning, weakens continuity between assessment and plan, and complicates demonstration of medical necessity.

Three Phases of Healing

Every wound is classified by its active biologic phase — Cleaning, Building, or Closing — based on objective wound-bed findings. Interventions are then selected to match the phase the wound is actually in, not the dressing category a clinician prefers.

Local & Systemic Impairment Drivers

At every visit, local barriers (pressure, edema, infection) and systemic barriers (perfusion, metabolic status, nutrition) are identified and documented. This makes delayed healing a visible, addressable problem rather than an unexplained one.

Defensible Medical Necessity

Organizing care around phase and impairment domains produces documentation that is complete, internally consistent, and clearly justifies advanced therapies. Regulators see reasoning; providers see continuity; patients see progress.

I strongly recommend this book as a reference for all who treat wounds.

— Paul Kim, DPM

The Model

Every wound encounter is structured around two questions: what phase is the wound in, and what is keeping it there?

Phases of Healing

Phase

Cleaning

Remove devitalized tissue, control bioburden, and prepare the wound bed for productive healing.

Phase

Building

Support granulation, matrix formation, and tissue development through the active reparative phase.

Phase

Closing

Drive epithelialization, contracture, and durable closure of the wound surface.

Healing Impairment Domains

Local Barriers

What the wound is sitting in

  • • Pressure & offloading
  • • Edema & venous congestion
  • • Infection & bioburden
  • • Moisture balance
  • • Mechanical trauma
Systemic Barriers

What the patient is bringing to it

  • • Perfusion & arterial supply
  • • Metabolic & glycemic status
  • • Nutrition & protein stores
  • • Immunologic competence
  • • Medication effects

Why It Matters

Complete, consistent documentation
Physiologic alignment between assessment and plan
Reduced phase–intervention mismatch
Clearer medical necessity for advanced therapies
Fewer redundant or incompatible dressing combinations
Continuity of care across providers

Chronic wound care is fundamentally a problem of impaired biology rather than product selection. This framework reframes chronic wound management as a dynamic process of biologic problem-solving — not a static process of product selection.

About the Author

Lonnie Lassiter, MD

Lonnie Lassiter, MD

Wound Care Specialist

Lonnie Lassiter, MD has spent his career caring for patients with complex acute and chronic wounds. This textbook is the distillation of that work — a practical reference grounded in daily clinical experience, designed for the clinicians who actually sit at the bedside.

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